The human body can synthesize creatine from amino acids methionine, arginine and glycine.  This metabolite is mainly synthesized in the liver although, the kidneys and pancreas also synthesis small amounts of the metabolite. Excess demands of creatine can be met by using creatine supplements which contains this metabolite in the form of creatine monohydrate. These supplements improve overall health and fitness levels, improves mental performance, increases rate of recovery after injury, increase muscle mass, stamina. Creatine supplements can enhance muscle growth by increasing protein synthesis and by causing muscle volumization wherein the supply of fluids to the muscle tissues is increased. When combined with exercise these help build better and stronger muscles. Fast muscle fibers, which are used for quick movements respond better to creatine supplementation when compared to slow muscle fibers which are used for exercise endurance. Creatine supplements are available in liquid creatine serum form and also in the form of powder which can be stirred into juice or water. They can cause side effects like gas, abdominal bloating, diarrhea, muscle strains, renal stress, and dehydration. The benefits of supplementation will disappear within one month of discontinuing use so it is necessary to continue supplementation for as long as possible.